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Protocol // Recovery_Science

NAC and Glutamate: Modulating the Craving Substrate

Researcher: Lead Research Board • AI Ethics Oversight Active

N-Acetyl Cysteine (NAC) serves as a precursor to glutathione and a potent modulator of the cystine-glutamate antiporter. In the context of stimulant use disorders, NAC has shown promise in restoring glutamate homeostasis in the nucleus accumbens, effectively reducing the intensity of signal-driven cravings.

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