Some symptoms are not a bad night to sleep off.

Stimulants can raise heart rate, blood pressure, and body temperature. Sleep loss, dehydration, exertion, unknown potency, other drugs, and existing health conditions can make the situation more dangerous. You do not need to know exactly what was taken before asking for help.

Call 911 now for

• Chest pressure or severe chest pain
• Trouble breathing, blue or gray lips, or very slow breathing
• A seizure, collapse, or inability to wake the person
• Very high body temperature, hot dry skin, severe confusion, or loss of coordination
• Signs of stroke: face drooping, arm weakness, sudden trouble speaking, sudden severe headache, or sudden loss of balance
• Extreme agitation, violent behavior, or psychosis that creates immediate danger

Tell dispatchers the location, symptoms, known substances, and whether the person is breathing. If opioids or fentanyl contamination may be involved, give naloxone if available and stay with the person. Naloxone does not reverse stimulant toxicity, but it can reverse an opioid overdose.

For a possible exposure without life-threatening symptoms

Call Poison Control at 1-800-222-1222. The service is free, confidential, and available 24/7 in the United States. Do not wait for symptoms to appear.

Reviewed against CDC overdose guidance and Poison Control.